- Full Time
- Memphis, Shelby County
St. Jude Children's Research Hospital at a glance
SEC filings mentioning "St. Jude Children's Research Hospital": 75 — search EDGAR
St. Jude Children's Research Hospital
Join St. Jude Children's Research Hospital in Memphis, Shelby County, as a Postdoctoral Research Associate in Chemical Biology and Therapeutics. This full-time position offers the opportunity to conduct cutting-edge research in drug discovery and chemical biology within a collaborative, multidisciplinary research environment at one of the nation's leading pediatric research institutions.
About the Role
The Chen Lab at St. Jude is seeking a talented postdoctoral researcher to contribute to groundbreaking studies in chemical biology and drug development. You'll work alongside experienced scientists to design, synthesize, and evaluate novel chemical compounds targeting key regulatory proteins in disease pathways. This role combines synthetic chemistry, molecular pharmacology, and translational research to advance therapeutic discovery for childhood diseases.
What You'll Do
- Design and characterize novel small-molecule inhibitors and degraders targeting nuclear receptors and cytochrome P450 enzymes
- Conduct biochemical and biophysical assays to evaluate compound efficacy and mechanism of action
- Perform cellular and molecular studies to validate chemical probes in relevant disease models
- Collaborate with team members across chemistry, biology, and computational disciplines to optimize lead compounds
- Analyze experimental data and contribute to manuscript preparation and scientific presentations
- Maintain detailed research records and comply with laboratory protocols and safety standards
What We're Looking For
- PhD in Chemistry, Chemical Biology, Pharmacology, Molecular Biology, or a closely related field
- Strong background in organic synthesis, medicinal chemistry, or chemical biology
- Experience with biochemical assays, cell-based screening, or molecular biology techniques
- Demonstrated ability to design and execute complex research projects independently
- Excellent written and verbal communication skills for collaboration and scientific dissemination
- Commitment to rigorous experimental practices and scientific integrity
About St. Jude Children's Research Hospital
St. Jude Children's Research Hospital is a leading pediatric research and treatment facility dedicated to advancing cures and treatments for children with catastrophic diseases through innovative research and clinical care.
How to Apply
To apply, complete your application directly on this page, or you'll be redirected to the employer's application platform to finish submitting there.
To apply for this job please visit www.adzuna.com.
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Working in Memphis, Shelby County
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Memphis is a city in Shelby County, Tennessee, United States, and its county seat. Situated along the Mississippi River, it had a population of 633,104 at the 2020 census, making it the second-most populous city in Tennessee, the fifth-most populous in the Southeast, and the 29th-most populous in the US. Memphis is the largest city proper on the Mississippi River and anchors the Memphis area that includes parts of Arkansas and Mississippi, the 45th-most populous metropolitan area in the U.S. with 1.34 million residents.
Tennessee, officially the State of Tennessee, is a landlocked state in the Southeastern region of the United States. It borders Kentucky to the north, Virginia to the northeast, North Carolina to the east, Georgia, Alabama, and Mississippi to the south, Arkansas to the southwest, and Missouri to the northwest. Tennessee is the 36th-largest by area and the 15th-most populous of the 50 states. Accor
- Elevation 91m (299 ft)
Source: Wikipedia (state)
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