Merck at a glance
merckgroup.com- Founded 1668
- Employees 56000
- Ticker MRK
- Revenue (FY2025) $65.01B
- Net income $18.25B
Investor research: Yahoo Finance · SEC filings
Source: Wikipedia

Merck
Join Merck as a Distinguished Scientist in Quantitative Biosciences and Nonclinical Pharmacology at our South San Francisco facility. This full-time position offers a unique opportunity to apply advanced quantitative methods to solve critical drug development challenges and shape the future of pharmaceutical innovation.
About the Role
This Distinguished Scientist role combines deep scientific expertise with leadership responsibility in quantitative biosciences and nonclinical pharmacology. You will drive strategic initiatives in drug discovery and development, applying cutting-edge quantitative approaches to pharmacological questions that directly impact patient outcomes. Based in South San Francisco, you'll work at the intersection of computational science and experimental pharmacology, influencing both immediate research priorities and long-term scientific direction.
What You'll Do
- Design and execute advanced quantitative pharmacology studies, including pharmacokinetic and pharmacodynamic analyses
- Develop mathematical models and computational frameworks to predict drug behavior and efficacy
- Lead scientific strategy for nonclinical studies supporting IND applications and regulatory submissions
- Collaborate across discovery, development, and regulatory teams to integrate quantitative insights into decision-making
- Mentor and guide scientists in quantitative methods and best practices
- Present complex pharmacological data and analysis to internal leadership and external scientific audiences
- Contribute to methodological innovations and improvements in bioscience research tools
What We're Looking For
- PhD in pharmacology, biopharmaceutics, quantitative biology, computational biology, or related scientific field
- Substantial experience in nonclinical pharmacology, pharmacokinetics, pharmacodynamics, or drug metabolism
- Demonstrated mastery of quantitative modeling, biostatistics, and data analysis techniques
- Deep knowledge of pharmaceutical development pathways and regulatory requirements
- Proven track record of scientific leadership and influence within cross-functional teams
- Exceptional problem-solving abilities and scientific judgment
- Strong written and verbal communication skills
About Merck
Merck is a global leader in pharmaceutical research and development, with over 100 years of commitment to scientific excellence and human health. Our South San Francisco location serves as a hub for innovative drug discovery and development, positioning us at the center of the Bay Area's thriving life sciences community.
How to Apply
To apply, complete your application directly on this page, or you'll be redirected to the employer's application platform to finish submitting there.
To apply for this job please visit www.adzuna.com.
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Working in South San Francisco, San Mateo County
Weather right now in South San Francisco, San Mateo County: checking… · Local time: · Air quality: · Daylight: · UV index: · Wind:
South San Francisco is a city in San Mateo County, California, United States, on the San Francisco Peninsula in the San Francisco Bay Area. The city is colloquially termed "South City". The population was 66,105 at the 2020 census.
California is a U.S. state in the Western United States that lies on the Pacific Coast. It borders Oregon to the north, and Nevada and Arizona to the east; it also shares an international border with the Mexican state of Baja California to the south. With over 39 million residents across an area of 163,696 square miles (423,970 km2), it is the largest U.S. state by population and third-largest by
Recent seismic activity: 1 earthquake (M4.5+) within 200km in the last 6 months — largest M4.6 near 1 km SE of Boulder Creek, CA. via USGS
- Elevation 6m (20 ft)
Source: Wikipedia (state)
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Accommodations: if you need a workplace accommodation to apply for or perform this job, see ADA.gov or EEOC.gov for guidance on your rights and how to request one.
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