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Principal Scientist, Toxicology & Pharmacology

  • Company: Shasqi
  • Location: US
  • Salary: $150,000–$180,000/yr
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  • Full Time
  • US
  • $150,000–$180,000/yr
  • Apply on company site
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  • $150,000–$180,000/yr

Shasqi at a glance

shasqi.com

SEC filings mentioning "Shasqi": 5search EDGAR

Federal funding recipient: largest known award $2.0M from the Department of Health and Human Services (started Sep 6, 2024) — via USAspending.gov

Antigen-targeted activation of topo1 inhibitors via click chemistry - abstract most drugs are administered systemically and spread throughout the body. due t…

Join Shasqi as a Principal Scientist, Toxicology & Pharmacology in a full-time, US-based position. We're seeking an experienced scientist to lead our research efforts, where cutting-edge science meets the mission of delivering powerful treatments precisely to tumors while protecting healthy tissue.

About the Role

Shasqi is advancing precision medicine by leveraging breakthrough science to create therapies that work where they're needed most. As Principal Scientist, you'll take a leadership role in evaluating the safety and efficacy profiles of our therapeutic candidates, guiding their development from preclinical stages through clinical advancement. Your expertise will be central to our ability to bring selective, potent treatments to patients.

What You'll Do

  • Lead preclinical and clinical toxicology and pharmacology studies to characterize candidate drugs and their mechanisms
  • Develop regulatory strategies and ensure compliance with FDA and international guidelines for investigational therapeutics
  • Collaborate cross-functionally with chemistry, biology, and clinical teams to optimize compound safety and efficacy
  • Direct research initiatives, mentor junior scientists, and foster a culture of scientific rigor and innovation
  • Prepare and present findings to internal and external stakeholders, including regulatory agencies
  • Contribute to peer-reviewed publications and scientific presentations advancing the field

What We're Looking For

  • PhD in Toxicology, Pharmacology, Chemistry, or a closely related discipline
  • 10+ years of experience in drug development, particularly in toxicology and pharmacology assessments
  • Demonstrated expertise in regulatory pathways and IND/NDA strategy
  • Strong track record of scientific leadership and mentoring
  • Excellent communication and project management skills
  • Passion for precision medicine and impact-driven science

About Shasqi

Shasqi is a biopharmaceutical company developing the next generation of targeted therapies. Our team combines diverse expertise unified by a single goal: delivering effective treatment where patients need it most, without unnecessary exposure to healthy cells. We're advancing precision oncology through innovative science.

How to Apply

To apply, complete your application directly on this page, or you'll be redirected to the employer's application platform to finish submitting there.

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Working in US

The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic consisting of 50 states and a federal capital district, Washington, D.C. The 48 contiguous states border Canada to the north and Mexico to the south, with the semi-exclave of Alaska in the northwest and the archipelago of Hawaii in the Pacific Ocean. The United States also asserts sovereignty over five major island territories and various uninhabited islands in Oceania and the Caribbean. It is a megadiverse country, with the world's th

🇺🇸 Relocation safety for US: Exercise Normal Cautionvia Warnely, CC BY 4.0

National unemployment rate in US: 4.2%via World Bank

Private-sector wage growth (year over year): 3.3%via FRED

National quits rate: 1.9%via FRED (BLS JOLTS)

GDP per capita in US: $90,027via World Bank

Consumer price inflation in US: 2.9% (annual) — via World Bank

Average hours worked per year in US: 1,800via OECD

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    Listing facts

    • Role Principal Scientist, Toxicology & Pharmacology
    • Employer Shasqi
    • Location US
    • Type Full Time
    • Pay (from listing) $150,000–$180,000/yr
    • Posted June 2, 2026
    • Apply by 2026-08-01
    • Country context US
    • Overview Full original description on this page (310 words; rewritten for clarity, not a teaser paste)

    Facts above come from this job record on Get A Job.AI — not copied from third-party review sites.

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