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Senior Machine Learning Engineer, AI Enablement

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  • Company: Genentech
  • Location: South San Francisco, San Mateo County
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Join Genentech as a Senior Machine Learning Engineer, AI Enablement in South San Francisco, where you'll architect machine learning solutions that accelerate drug discovery and advance healthcare innovation at a world-class biotech organization.

About the Role

We're seeking an experienced Senior Machine Learning Engineer to lead the design, development, and deployment of AI and machine learning systems that enable scientists and researchers across the organization. You'll take ownership of building robust, scalable ML infrastructure and platforms that integrate into our research and development workflows, driving measurable impact on drug development timelines and scientific outcomes.

What You'll Do

  • Design and implement machine learning models and algorithms that solve complex problems in drug discovery, molecular biology, and healthcare applications
  • Build and maintain ML infrastructure, data pipelines, and production systems that support research teams across the organization
  • Collaborate with scientists, computational biologists, and software engineers to translate research requirements into scalable ML solutions
  • Optimize model performance, evaluate trade-offs between accuracy and computational efficiency, and implement best practices for model governance and validation
  • Mentor junior engineers and contribute to technical standards and architectural decisions for AI/ML systems
  • Stay current with advances in machine learning, deep learning, and AI methodologies, and evaluate emerging technologies for organizational adoption

What We're Looking For

  • 5+ years of professional experience building and deploying machine learning systems in production environments
  • Strong foundation in machine learning, statistics, and software engineering best practices
  • Proficiency with ML frameworks, data processing tools, and cloud platforms
  • Demonstrated ability to work cross-functionally with domain experts and translate complex requirements into technical solutions
  • Excellent problem-solving skills and attention to quality in both code and scientific rigor
  • Experience in life sciences, healthcare, or research environments is a plus

About Genentech

Genentech is a pioneering biotechnology company dedicated to advancing science and expanding access to transformative healthcare solutions. We believe that great science drives innovation, and we invest in talented teams that push the boundaries of what's possible in medicine and biology.

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Listing facts

  • Role Senior Machine Learning Engineer, AI Enablement
  • Employer Genentech
  • Location South San Francisco, San Mateo County
  • Type Full Time
  • Posted July 1, 2026
  • Apply by 2026-08-02
  • Country context US
  • Overview Full original description on this page (347 words; rewritten for clarity, not a teaser paste)

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Senior Machine Learning Engineer, AI Enablement Genentech · South San Francisco, San Mateo County