- Company: Ionis
- Location: Carlsbad, San Diego County
- Salary: $216,439–$265,200/yr
- Full Time
- Carlsbad, San Diego County
- $216,439–$265,200/yr
- Apply on company site
- $216,439–$265,200/yr
Ionis at a glance
ionis-group.com- Founded 1980
SEC filings mentioning "Ionis": 2,035 — search EDGAR
Source: Wikipedia
Join Ionis as Director of Drug Metabolism, Pharmacokinetics & Clinical Pharmacology, leading our DMPK strategy in Carlsbad, San Diego County. This full-time leadership role shapes the scientific foundation for our RNA-targeted medicine development.
About the Role
As Director of DMPK, you'll lead a function critical to bringing innovative medicines to patients. You'll oversee pharmacokinetic studies, clinical pharmacology assessments, and drug metabolism investigations that inform our drug development programs. This position combines hands-on scientific leadership with strategic oversight of our DMPK initiatives across multiple therapeutic programs.
What You'll Do
- Direct pharmacokinetic and drug metabolism studies, ensuring scientific rigor and regulatory compliance
- Lead clinical pharmacology evaluations that support IND applications, clinical trials, and regulatory submissions
- Manage and mentor a team of DMPK scientists and pharmacologists
- Collaborate with drug discovery, development, and clinical teams to define DMPK strategies
- Stay current with evolving regulatory guidance and scientific best practices in pharmacokinetics
- Contribute to the advancement of Ionis' RNA-targeted medicine platform
What We're Looking For
- Advanced degree (Ph.D. or M.D.) with significant experience in drug metabolism and pharmacokinetics
- Leadership experience managing scientists and directing DMPK functions in biotech or pharmaceutical settings
- Deep knowledge of pharmacokinetic principles, drug-drug interactions, and clinical pharmacology
- Proven track record supporting IND applications and clinical regulatory submissions
- Strong scientific communication skills and ability to influence cross-functional teams
- Experience with or knowledge of RNA-targeted or novel therapeutic modalities is a plus
About Ionis
For over three decades, Ionis has been dedicated to creating medicines that change lives for patients with serious diseases. With our base in Carlsbad and additional operations in Boston and Dublin, we pioneer RNA-targeted approaches that advance the frontier of therapeutic medicine.
How to Apply
To apply, complete your application directly on this page, or you'll be redirected to the employer's application platform to finish submitting there.
To apply for this job please visit www.adzuna.com.
Explore Ionis online
What people say about Ionis
- Fear of radiation can be irrational
- Droid has been rooted
- Ionising radiation and risk of death from leukaemia and lymphoma
- U.S. GDP Shrank in Q1 2015
Recent news
- AstraZeneca, Ionis report major trial failure with heart disease drug - STAT
- Roche ends 2 Huntington’s disease programs, including Ionis-partnered tominersen - Fierce Biotech
- Ionis Pharmaceuticals Drops Another 9% as Bad News Piles Up - Yahoo Finance
- The Long Climb Back For Ionis Stock - Trefis
- Ionis and AstraZeneca: Shares Tank as Phase 3 ATTR-CM Trial Falls Short of Expectations - Morningstar
Aggregated from public discussions and news; opinions are the authors’ own.
Working in Carlsbad, San Diego County
Weather right now in Carlsbad, San Diego County: checking… · Local time: · Air quality: · Daylight: · UV index: · Wind: · Pollen:
California is a U.S. state in the Western United States that lies on the Pacific Coast. It borders Oregon to the north, and Nevada and Arizona to the east; it also shares an international border with the Mexican state of Baja California to the south. With over 39 million residents across an area of 163,696 square miles (423,970 km2), it is the largest U.S. state by population and third-largest by
🇺🇸 Relocation safety for US: Exercise Normal Caution — via Warnely, CC BY 4.0
National unemployment rate in US: 4.2% — via World Bank
Private-sector wage growth (year over year): 3.3% — via FRED
National quits rate: 1.9% — via FRED (BLS JOLTS)
GDP per capita in US: $90,027 — via World Bank
Consumer price inflation in US: 2.9% (annual) — via World Bank
Average hours worked per year in US: 1,800 — via OECD
Median household income in San Diego County: $102,285 — via US Census ACS / Data USA
Recent seismic activity: 2 earthquakes (M4.5+) within 200km in the last 6 months — largest M4.9 near 20 km NNE of Indio, CA. via USGS
Nearby history: Carlsbad Santa Fe Depot, listed 1993 (192m away) — via National Register of Historic Places
Typical climate: average high 66°F / low 54°F year-round (summers around 69°F, winters around 45°F) — via NOAA 1991-2020 Normals
Walkability: Above average walkable (15.2/20) — via EPA National Walkability Index
Typical rent nearby: $2,459/mo (1BR) · $3,001/mo (2BR) — via HUD Fair Market Rents
- Elevation 18m (59 ft)
Source: Wikipedia (state)
Job details above are provided by the employer/source. The sections on this page are compiled from public data sources with AI assistance.
Accommodations: if you need a workplace accommodation to apply for or perform this job, see ADA.gov or EEOC.gov for guidance on your rights and how to request one.
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