The OpenAI Foundation is building out its life sciences program to help accelerate progress on curing diseases and improving human health. The program’s initial focus areas include AI for Alzheimer’s, Public Data for Health, and High-Burden Diseases. We are looking for a Program Officer, High – Burden Diseases to help build this work from the ground up. We define High-Burden Diseases as those that affect large populations and have significant public health impacts.

Your Responsibilities

Identify and prioritize high-impact projects in the field of High-Burden Diseases, working closely with researchers, policymakers, and other stakeholders.
Develop and manage partnerships with organizations, institutions, and individuals to advance research and development efforts in the field.
Monitor and evaluate project progress, ensuring alignment with program goals and objectives.
Collaborate with cross-functional teams to identify opportunities for innovation and collaboration within the High-Burden Diseases space.

Requirements

A minimum of 5 years of relevant experience in public health, healthcare policy, or a related field.
Experience working on projects involving high-burden diseases such as HIV/AIDS, tuberculosis, malaria, and others is preferred.
Strong project management skills with the ability to prioritize multiple tasks and meet deadlines.
Excellent communication and interpersonal skills, including experience in stakeholder engagement and collaboration.
Familiarity with data analysis tools and public health research methodologies.

About Open Roles

Open Roles is dedicated to advancing the field of life sciences through innovative projects that address high-burden diseases. Our team consists of experts from diverse backgrounds who are committed to making a positive impact on global health.

Applying for This Role

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Working in San Francisco, California

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California is a U.S. state in the Western United States that lies on the Pacific Coast. It borders Oregon to the north, and Nevada and Arizona to the east; it also shares an international border with the Mexican state of Baja California to the south. With over 39 million residents across an area of 163,696 square miles (423,970 km2), it is the largest U.S. state by population and third-largest by

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National unemployment rate in US: 4.2% — via World Bank

Private-sector wage growth (year over year): 3.1% — via FRED

National quits rate: 2.0% — via FRED (BLS JOLTS)

Weekly initial unemployment claims: 206,000 — via FRED

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Typical rent nearby: $2,977/mo · $3,604/mo — via HUD Fair Market Rents

Elevation 38m (125 ft)

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Listing facts

Role Program Officer, High – Burden Diseases
Employer Open Roles
Location San Francisco, California
Type Full Time
Pay (from listing) $220,000–$330,000/yr
Posted August 21, 2026
Apply by September 20, 2026
Country United States
Overview Full job description on this page (330 words)

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