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Expect depth on biologics discovery–to–process translation, stakeholder alignment, and examples of senior scientific judgment under ambiguity.
Strong fit if you lead at principal/senior scientific level in biologics, thrive as an integrator (not only a single-lab expert), and prefer on-site collaboration in Spring House, Montgomery County, PA.
As Senior Principal Scientist, Biologics Discovery Process Research Integrator at Janssen Research & Development (Spring House, on-site), a typical day centers on connecting discovery science with process research: aligning cross-functional teams, reviewing experimental and process data, and driving integrated decisions so biologics candidates move with clear technical rationale.
Role emphasis is scientific leadership in biologics discovery and process integration—not a fixed cert path. Available credential resources for this listing: none listed.
No—the listing marks remote as off; plan for on-site work in Spring House, Montgomery County, Pennsylvania.
A senior principal scientist acting as integrator across biologics discovery and process research—alignment, data synthesis, and cross-team decisions more than isolated bench work alone.
The employer is shown as 6084-Janssen Research & Development Legal Entity; no separate company profile data was supplied for this enricher run.
Join 6084-Janssen Research & Development Legal Entity as a Senior Principal Scientist, Biologics Discovery Process Research Integrator in Spring House, Montgomery County. This is a full-time position for a strategic scientific leader ready to drive innovation at the intersection of biologics discovery and process development. About the Role As Senior Principal Scientist, you will serve as a key integrator between discovery research teams and process development functions, translating early-stage biologics insights into manufacturable, scalable solutions. You'll drive cross-functional collaboration, establish scientific frameworks that accelerate discovery-to-clinic timelines, and shape the strategic direction of our biologics pipeline. What You'll Do Lead biologics discovery initiatives from concept through preclinical validation, ensuring manufacturability and regulatory compliance from the start Integrate molecular biology, cell engineering, and bioprocess science to optimize candidate selection and early development strategy Mentor and guide scientific teams, fostering a culture of innovation and rigorous problem-solving Develop and communicate scientific strategies for complex biologic programs to senior leadership and external stakeholders Champion process improvements and emerging technologies that enhance discovery productivity and reduce time to candidates Collaborate with regulatory affairs and quality teams to ensure all research aligns with development and compliance standards What We're Looking For PhD or equivalent advanced degree in molecular biology, biochemistry, bioengineering, or related discipline 10+ years of progressively senior experience in biologics discovery, process development, or biotech research Proven expertise in antibody engineering, cell therapy, or other advanced biologics modalities Track record of leading cross-functional teams and translating early research into development programs Strong scientific judgment, strategic thinking, and ability to communicate complex concepts clearly Familiarity with regulatory pathways (IND, BLA) and manufacturing scale-up considerations About 6084-Janssen Research & Development Legal Entity Part of Johnson & Johnson, Janssen R&D is committed to discovering and developing medicines that address some of the world's most challenging diseases. Based in Spring House, our team combines cutting-edge science with a mission-driven culture to transform healthcare. How to Apply Apply through this listing to be considered for the Senior Principal Scientist, Biologics Discovery Process Research Integrator position.
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