Ground every answer in facts on this page and the original listing. We never invent Glassdoor-style reviews or salaries that are not in our data.
Strong fit for physician-scientists or clinical leaders with early development depth in specialty/rare disease who want portfolio impact at a commercial rare-disease biotech (BMRN).
As Senior Medical Director, Early Clinical Development at BioMarin, you would shape first-in-human and early POC strategy for rare-disease assets—protocol design, safety and dose rationale, investigator engagement, and cross-functional work with clinical ops, regulatory, and translational science—aligned to BioMarin’s enzyme and genetic-medicine portfolio.
Deep clinical development experience (Phase 1/2), rare-disease or metabolic indication fluency, protocol and safety leadership, regulatory interaction readiness, and cross-functional influence. No certification list is provided in the data.
The listing is United States and not remote; headquarters is San Rafael, CA, but a specific site is not in the data.
Rare-disease biotech, especially enzyme replacement therapies, with first-to-market history in MPS I and PKU.
No salary bands or Glassdoor/Indeed-style ratings are in the provided data.
Website: biomarin.com
BioMarin Pharmaceutical Inc. is an American biotechnology company headquartered in San Rafael, California. It has offices and facilities in the United States, South America, Asia, and Europe. BioMarin's core business and research are in enzyme replacement therapies (ERTs). BioMarin was the first company to provide therapeutics for mucopolysaccharidosis type I, by manufacturing laronidase. BioMarin was also the first company to provide therapeutics for phenylketonuria (PKU).
Public cache only — not an employee review.
Here is the rewritten job description as semantic HTML: BioMarin Pharmaceutical is seeking a Senior Medical Director, Early Clinical Development to help advance breakthrough therapies for rare, genetically defined diseases across the United States. This is a pivotal leadership opportunity to shape the early-stage clinical strategy behind life-changing medicines. About the Role As Senior Medical Director, Early Clinical Development at BioMarin Pharmaceutical, you will provide clinical and scientific leadership during the earliest phases of drug development. Based in the US, this full-time, on-site position places you at the heart of translating cutting-edge science into first-in-human studies that bring hope to patients living with rare conditions. Key Responsibilities Direct the medical and scientific strategy for early-phase (Phase 1 and 2) clinical programs. Serve as the clinical lead on cross-functional development teams, guiding study design and protocol development. Oversee the safety, integrity, and scientific rigor of ongoing early clinical trials. Interpret emerging clinical data to inform go/no-go decisions and program direction. Partner with regulatory, research, and commercial colleagues to progress candidates through the development pipeline. Contribute clinical expertise to interactions with health authorities, investigators, and key external stakeholders. Qualifications Medical degree (MD or equivalent) with relevant clinical and therapeutic experience. Substantial background in early clinical development within the biotechnology or pharmaceutical industry. Strong command of clinical trial design, drug safety, and the regulatory landscape. Proven ability to lead multidisciplinary teams and drive complex programs forward. Excellent scientific judgment, communication, and collaborative skills. About BioMarin Pharmaceutical Founded in 1997, BioMarin is a global leader in rare disease biotechnology, devoted to developing medicines that make a meaningful difference in patients' lives. The company has built a respected portfolio of therapies for genetically defined conditions, including treatments for achondroplasia — the most common form of dwarfism — and PKU. Driven by science and a deep sense of purpose, BioMarin's teams pursue innovative treatments where few options previously existed. How to Apply Ready to drive the future of rare disease therapies? View the full listing and apply for the Senior Medical Director, Early Clinical Development role at BioMarin Pharmaceutical via Adzuna.
Generated for personal interview prep · 2026-07-16 UTC · getajob.ai