Research Scientist/Engr 4

The University of Washington is seeking a Research Scientist/Engineer 4 to advance cutting-edge structural biology aimed at developing vaccines and therapeutics against human pathogens. This full-time, on-site position is based in King County and supports an international research mission at the forefront of immunogen science.

About the Role

As a Research Scientist/Engineer 4 at the University of Washington, you will contribute to a research program focused on the structural and molecular characterization of viral glycoproteins. Your work will combine single particle cryo-electron microscopy (cryo-EM) and X-ray crystallography with computational and structure-guided immunogen design, drawing on virology, biochemistry, and biophysics to inform the next generation of vaccines and therapeutics.

Key Responsibilities

• Apply structure-based and machine-learning approaches to design novel immunogens targeting human pathogens.
• Conduct single particle cryo-EM studies to resolve the architecture of viral glycoproteins.
• Perform X-ray crystallization and structure determination of protein targets of interest.
• Carry out biochemical and biophysical characterization to support immunogen development.
• Collaborate across virology and structural biology efforts to translate findings toward vaccine and therapeutic candidates.

Qualifications

• Demonstrated expertise in single particle cryo-electron microscopy and/or X-ray crystallography of macromolecules.
• Strong background in virology, biochemistry, and biophysics.
• Experience with structure-based and computational or machine-learning methods for protein and immunogen design.
• Ability to work independently and contribute within a collaborative, multidisciplinary research team.

About University of Washington

The University of Washington is one of the world's leading public research institutions, recognized for its impact in the life sciences and global health. Researchers here pursue ambitious projects that translate fundamental discovery into real-world solutions for human disease, working alongside accomplished colleagues across structural biology, immunology, and virology.

How to Apply

If you are ready to bring your structural biology and immunogen design expertise to a mission-driven team in King County, we encourage you to apply for the Research Scientist/Engineer 4 role at the University of Washington. View the full listing and submit your application to be considered for this full-time, on-site opportunity.