Zyphra at a glance
SEC filings mentioning "Zyphra": 2 — search EDGAR
Zyphra
Zyphra is an artificial intelligence company based in San Francisco, California.
The Role:
As a Lead Frontend Engineer, you’ll lead the design and development of the user-facing side of our agentic system, shaping how users interact with AI across their desktop, browser, and filesystem. You’ll work across interface design, component libraries, and frontend infrastructure to craft seamless, accessible, and intuitive user experiences. You’ll work closely with engineers, ML researchers, and backend teams to bring intelligent agents to life in a way that’s beautifully simple and deeply useful.
You’ll Work Across:
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Design and development of browser-based and desktop interfaces
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Building and maintaining component libraries and styling systems
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Researching and refining user flows based on real-world usage and feedback
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Prototyping and implementing UI features in collaboration with ML, backend, and systems teams
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Making a complex AI product feel simple, accessible, and empowering for a wide range of users
What We’re Looking For / Requirements:
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Strong frontend engineering skills with fluency in HTML, CSS, and JavaScript/TypeScript
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Experience with modern frontend frameworks such as React
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Demonstrated attention to UI detail and usability, with a user-first mindset
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Ability to prototype and iterate quickly, both in code and with design tools like Figma
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Experience designing and developing responsive, accessible, and high-performance interfaces
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Strong intuition for HCI principles, accessibility, and visual clarity
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Excellent collaboration and communication skills—especially with engineers, designers, and ML researchers
Qualifications / Additional Skills:
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Experience designing or building browser extensions or desktop applications (e.g., Electron, Tauri)
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Experience with mobile platforms and responsive design (not required but helpful)
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Prior work on products involving complex workflows, automation, or agentic behavior
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Interest or experience in backend development, APIs, or AI systems to better interface with the full stack
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Familiarity with accessibility standards and inclusive design best practices
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A track record of launching polished and user-loved products
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Passion for systems-level thinking: building reusable design systems, libraries, and scalable patterns
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A clear, opinionated eye for elegant design and user delight
Why Work at Zyphra:
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Our research methodology is grounded in methodical, step-by-step approaches to ambitious goals. Both deep research and engineering excellence are equally valued
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We strongly value new and crazy ideas and are very willing to bet big on new ideas
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We move as quickly as we can; we aim to minimize the bar to impact as low as possible
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We all enjoy what we do and love discussing AI
Benefits and Perks:
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Comprehensive medical, dental, vision, and FSA plans
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Competitive compensation and 401(k) plan
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Relocation and immigration support on a case-by-case basis
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In-office snacks and meals provided
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Unlimited PTO and company holidays
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In-person team in San Francisco with a collaborative, high-energy environment
To apply for this job please visit jobs.ashbyhq.com.
Terms used in this posting
- PTO
- Paid Time Off — vacation, personal, or sick days you can take while still being paid.
Explore Zyphra online
Working in San Francisco, California
Weather right now in San Francisco, California: checking… · Local time: · Air quality: · Daylight: · UV index: · Wind:
San Francisco, officially the City and County of San Francisco, is the fourth-most populous city in California and the 17th-most populous in the United States, with a population of 826,079 in 2025. Among U.S. cities with a population of 200,000 or more, San Francisco is ranked first by per capita income, second by population density, and sixth by aggregate income as of 2024. Some 4.6 million residents live in the city's metropolitan statistical area, which is the 13th-largest in the United States. Around 9.2 million live in the San Jose–San Francisco–Oakland combined statistical area, the fift
California is a U.S. state in the Western United States that lies on the Pacific Coast. It borders Oregon to the north, and Nevada and Arizona to the east; it also shares an international border with the Mexican state of Baja California to the south. With over 39 million residents across an area of 163,696 square miles (423,970 km2), it is the largest U.S. state by population and third-largest by
🇺🇸 Relocation safety for US: Exercise Normal Caution — via Warnely, CC BY 4.0
National unemployment rate in US: 4.2% — via World Bank
Recent seismic activity: 2 earthquakes (M4.5+) within 200km in the last 6 months — largest M5.6 near 11 km N of Redwood Valley, CA. via USGS
- Elevation 38m (125 ft)
Source: Wikipedia (state)
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Accommodations: if you need a workplace accommodation to apply for or perform this job, see ADA.gov or EEOC.gov for guidance on your rights and how to request one.
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